MOLECULAR CELL BIOLOGY AND GENET
OCTOBER 2011 P/ID 40321/PZLC
Time : Three hours Maximum : 100 marks
PART A — (10 × 2 = 20 marks)
Answer ALL questions.
All questions carry equal marks.
Each answer should not exceed 50 words.
Define/Explain the following :
1. Unit membrane.
2. Heterochromatin.
3. Spindle fibre.
4. Metatasis.
5. Map unit.
6. Regulator gene.
7. Lysogenic cycle.
8. B-DNA.
9. Initiation codon.
10. Radio isotope.
PART B — (5 × 6 = 30 marks)
Answer ALL questions.
All questions carry equal marks.
Each answer should not exceed 250 words.
11. (a) What is active transport? Explain.
Or
(b) Illustrate the ultra structure of mitochondria.
12. (a) What is a Cell cycle? Explain the molecular
events.
Or
(b) List any six characteristics of a cancer cells.
13. (a) Describe any two oncogenic viruses.
Or
(b) Discuss one gene one polypeptide concept.
14. (a) Give an account of DNA repair mechanism.
Or
(b) Write on the Trimming of introns.
P/ID 40321/PZLC 3
15. (a) Explain GAL operon system.
Or
(b) Describe the radiation sources.
PART C — (5 × 10 = 50 marks)
Answer ALL questions.
All questions carry equal marks.
Each answer should not exceed 500 words.
16. (a) Explain Nuclear transplantation experiments
and their significance.
Or
(b) Illustrate and explain the structure and
functions of lamp–brush and polytene
chromosome.
17. (a) Write an account on spindle organization and
chromosome movements.
Or
(b) Discuss the Theories of Carcinogenesis.
18. (a) Illustrate and explain Bacterial conjugation
and its importance.
Or
(b) Explain chromosome mapping in Eukaryotes.
P/ID 40321/PZLC 4
19. (a) What is Transcription, explain the molecular
events of this process.
Or
(b) Describe any two evidences of regulation of
gene action.
20. (a) Write an account on Inborn–errors of
Metabolism with reference to
Phenylketoneuria.
Or
(b) Discuss the radiational hazards to genetic
material and its origin.
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