Are you searching for alagappa university question papers? In biotechnology degree the fourth elective paper is FUNCTIONAL GENOMICS. In this question paper 2013 onwards regulation. This question paper contains 75 marks.
Alagappa University
M.Sc. DEGREE EXAMINATION, APRIL 2015
Biotechnology
Elective IV — FUNCTIONAL GENOMICS
(CBCS – 2013 onwards)
Time : 3 Hours Maximum : 75 Marks
Part A (10 x 2 = 20)
Answer all questions.
All questions carry equal marks.
1. Differentiate primer and probe.
2. ORF.
3. Microarray.
4. NMR.
5. Proteome.
6. GFP.
7. Pathogen.
8. C. elegans.
9. High throughput screening.
10. Drug target.
Part B (5 x 5 = 25)
Answer all questions choosing either (a) or (b).
11. (a) Write short notes on Human Genome Project.
Or
(b) Explain the principle and applications of RT-PCR.
12. (a) Explain about protein microarray.
Or
(b) How will you analyze the protein by 2-D gel electrophoresis?
13. (a) Give an account on protein – protein interactions.
Or
(b) Discuss about the role of proteomics in diseases.
14. (a) Discuss about the environmentally significant microorganisms.
Or
(b) Write short notes on the human microbial pathogens.
15. (a) Write notes on pharmacogenetics.
Or
(b) How will you identify the drug targets?
Part C (3 x 10 = 30)
Answer any three questions.
16. Write about the standard protocol of differential gene expression and analysis methods.
17. Illustrate the analysis of protein by Mass spectroscopy.
18. Explain the followings with clear illustrations
(a) Yeast two—hybrid system
(b) phage display.
19. Discuss the functional genomic analysis of bacterial pathogens.
20. How will you develop drugs by using pharmacogenetics approach?
Alagappa University
M.Sc. DEGREE EXAMINATION, APRIL 2015
Biotechnology
Elective IV — FUNCTIONAL GENOMICS
(CBCS – 2013 onwards)
Time : 3 Hours Maximum : 75 Marks
Part A (10 x 2 = 20)
Answer all questions.
All questions carry equal marks.
1. Differentiate primer and probe.
2. ORF.
3. Microarray.
4. NMR.
5. Proteome.
6. GFP.
7. Pathogen.
8. C. elegans.
9. High throughput screening.
10. Drug target.
Part B (5 x 5 = 25)
Answer all questions choosing either (a) or (b).
11. (a) Write short notes on Human Genome Project.
Or
(b) Explain the principle and applications of RT-PCR.
12. (a) Explain about protein microarray.
Or
(b) How will you analyze the protein by 2-D gel electrophoresis?
13. (a) Give an account on protein – protein interactions.
Or
(b) Discuss about the role of proteomics in diseases.
14. (a) Discuss about the environmentally significant microorganisms.
Or
(b) Write short notes on the human microbial pathogens.
15. (a) Write notes on pharmacogenetics.
Or
(b) How will you identify the drug targets?
Part C (3 x 10 = 30)
Answer any three questions.
16. Write about the standard protocol of differential gene expression and analysis methods.
17. Illustrate the analysis of protein by Mass spectroscopy.
18. Explain the followings with clear illustrations
(a) Yeast two—hybrid system
(b) phage display.
19. Discuss the functional genomic analysis of bacterial pathogens.
20. How will you develop drugs by using pharmacogenetics approach?
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