Solapur University
B.Sc. – III (Semester – VI) Examination, 2015
GENETIC ENGINEERING – APPLICATIONS (Biotechnology)
Day and Date : Monday, 6-4-2015 Max. Marks : 50
Time : 11.00 a.m. to 1.00 p.m.
N.B. : 1) All questions are compulsory.
2) Figures to the right indicate full marks.
1. Rewrite the following sentence by using appropriate alternative. 10
1) Golden rice is trangenic crop of the future with the following improved trait
________________
a) Insect resistance
b) High protein content
c) High Vit. A content
d) High lysin content
2) A genetically engineered microorganism used successfully in bioremediation
_______________
a) Trichoderma b) Bacillus
c) Xanthomonas d) Pseudomonas
3) Dolly the first animal produced through cloning is ____________
a) Camel b) Rat
c) Cow d) Sheep
4) Gene cloning refers to ______________
a) Production of large number of copies of gene being cloned
b) Production of asexual progeny from a single individual or a cell
c) Both a) and b)
d) None of these
SLR-M – 59 -2-
5) Two bacteria found to be very useful in genetic engineering experiment are
__________
a) Nitrobacter and Azatobacter
b) Rizobium and Diplococcus
c) Nitrosomonas and kliebsiella
d) Escherichia and Agrobactarium
6) ______________ organism used for alcohol production
a) Xanthomonas b) Zymomonas
c) Mycobactarium d) None of these
7) Xanthum gum produced from _______________
a) Pesudomonas b) Mycobactarium
c) Xanthomonas d) None of these
8) Transgenic mice used to treat ______________
a) Alzimer’s disease b) Cholera
c) Headache d) Both a) and b)
9) Inhibition of translation by using single stranded nucleotide called as
____________
a) Antigene therapy b) Antisense therapy
c) Nucleic acid therapy d) Gene therapy
10) Nif genes were first isolated from the clone banks of ____________
a) E. Coli b) Pesudomonas
c) K. pneumonia d) S. aureus
2. Answer the following (any 5) : 10
1) Antisense RNA
2) Antisense oligonucleotide
3) Define subunit vaccine
4) Gene therapy for cystic fibrosis
5) Tooth and mouth diseases
6) Modification of food plant taste eg. sweetness.
-3- SLR-M – 59
3. A) Answer the following (any 2) : 6
1) Write a note on Transgenic mice.
2) Write in brief plant act as bioreactor for carbohydrates.
3) Write in brief dignosis method of malaria.
B) Write a note on Monoclonal antibodies in treatment of brain tumor. 4
4. Answer the following (any 2) : 10
1) Write a note on microbial degradation of Xenobiots.
2) Gene therapy for cystic fibrosis.
3) Write note on Interfering RNA.
5. Answer the following (any 2) : 10
1) With suitable examples describe genetic engineering in plants.
2) Write a note on herbicide resistance.
3) Synthesis of any one noval antibiotic.
B.Sc. – III (Semester – VI) Examination, 2015
GENETIC ENGINEERING – APPLICATIONS (Biotechnology)
Day and Date : Monday, 6-4-2015 Max. Marks : 50
Time : 11.00 a.m. to 1.00 p.m.
N.B. : 1) All questions are compulsory.
2) Figures to the right indicate full marks.
1. Rewrite the following sentence by using appropriate alternative. 10
1) Golden rice is trangenic crop of the future with the following improved trait
________________
a) Insect resistance
b) High protein content
c) High Vit. A content
d) High lysin content
2) A genetically engineered microorganism used successfully in bioremediation
_______________
a) Trichoderma b) Bacillus
c) Xanthomonas d) Pseudomonas
3) Dolly the first animal produced through cloning is ____________
a) Camel b) Rat
c) Cow d) Sheep
4) Gene cloning refers to ______________
a) Production of large number of copies of gene being cloned
b) Production of asexual progeny from a single individual or a cell
c) Both a) and b)
d) None of these
SLR-M – 59 -2-
5) Two bacteria found to be very useful in genetic engineering experiment are
__________
a) Nitrobacter and Azatobacter
b) Rizobium and Diplococcus
c) Nitrosomonas and kliebsiella
d) Escherichia and Agrobactarium
6) ______________ organism used for alcohol production
a) Xanthomonas b) Zymomonas
c) Mycobactarium d) None of these
7) Xanthum gum produced from _______________
a) Pesudomonas b) Mycobactarium
c) Xanthomonas d) None of these
8) Transgenic mice used to treat ______________
a) Alzimer’s disease b) Cholera
c) Headache d) Both a) and b)
9) Inhibition of translation by using single stranded nucleotide called as
____________
a) Antigene therapy b) Antisense therapy
c) Nucleic acid therapy d) Gene therapy
10) Nif genes were first isolated from the clone banks of ____________
a) E. Coli b) Pesudomonas
c) K. pneumonia d) S. aureus
2. Answer the following (any 5) : 10
1) Antisense RNA
2) Antisense oligonucleotide
3) Define subunit vaccine
4) Gene therapy for cystic fibrosis
5) Tooth and mouth diseases
6) Modification of food plant taste eg. sweetness.
-3- SLR-M – 59
3. A) Answer the following (any 2) : 6
1) Write a note on Transgenic mice.
2) Write in brief plant act as bioreactor for carbohydrates.
3) Write in brief dignosis method of malaria.
B) Write a note on Monoclonal antibodies in treatment of brain tumor. 4
4. Answer the following (any 2) : 10
1) Write a note on microbial degradation of Xenobiots.
2) Gene therapy for cystic fibrosis.
3) Write note on Interfering RNA.
5. Answer the following (any 2) : 10
1) With suitable examples describe genetic engineering in plants.
2) Write a note on herbicide resistance.
3) Synthesis of any one noval antibiotic.
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