Monday, November 30, 2015

1.1 : PHARMACEUTICS – I,First Year B.Pharmacy,University Of Pune Question Paper,2012 Question Paper

University Of Pune Question Paper
First Year B.Pharmacy Examination, 2012
1.1 : PHARMACEUTICS – I(2008 Pattern)
Time : 3 Hours Max. Marks : 80
Instructions : 1) Answer to the two Sections should be written in separate
books.
2) Neat diagrams must be drawn wherever necessary.
SECTION – I
1. Define dosage form. Classify dosage form on the basis of route of administration
with suitable example. Also explain need to design dosage form. 10
OR
What are the clinical trials ? Explain phases of clinical trials in detail.
2. Answer the following (any 5) : 15
a) Briefly write about the types of containers.
b) Explain any two methods to enhance solubility of poorly water soluble drugs.
c) Define preformulation and explain bulk density and angle of repose.
d) Mention applications of Radiopharmaceuticals.
e) What is Bioavailability and Bioequivalence ?
f) Explain Sidha and Unani as alternative system of medicine.
g) What guidelines under the GMP to be followed by the pharmaceutical industry ?
3. Write a short note on (any three) : 15
a) Steps for new drug application
b) NDDS
c) Development of IP
d) Scope of pharmaceutics
e) Glass as packaging material.
SECTION – II
1. What is need of Granulation ? Explain different methods of granulation. 10
OR
What is Solution ? Explain in detail the factors affecting rate of solutions.
2. Answer the following (any 5) : 15
a) What are Elixirs ? Explain two methods of preparation of elixirs.
b) Define sieve number. What are the different grades of powder as per I.P. ?
c) What is size reduction ? Mention the factors affecting size reduction.
d) Explain in brief powder mixing mechanism.
e) Write in brief about propeller mixer.
f) Write in brief about the factors which affects rate of filtration
g) Explain rotary drum dryer.
3. Write a short note on (any three) : 15
a) Size distribution methods
b) Dusting powders
c) Fluid energy mill
d) Pouch filling machine
e) Tumbler mixer.
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B
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