University Of Pune Question Paper
Second Year B.Pharmacy Examination, 2013
(2008 Pattern)
2.7 : PHARMACOLOGY – I (Including Pathophysiology)
Time : 3 Hours Max. Marks : 80
Note : 1) All questions are compulsory.
2) Answer to the two Sections should be written in separate
answer books.
3) Neat labelled diagrams must be drawn wherever
necessary.
4) Black figures to the right indicate full marks.
SECTION – I
1. Define bioavailabilty of drugs. Discuss the factors affecting bioavailability. 10
OR
Classify anti – coagulants. Discuss the pharmacology of Warfarin.
2. Solve any five of the following : 15
i) Write the characteristics of dose response curve(DRC). Explain potency
and efficacy of drugs using DRCs.
ii) Write advantages and disadvantages of oral route of drug administration.
iii) Define apparent volume of distribution (Vd). Explain clinical significance of
Vd. of drug.
iv) Write a note on Vitamin-K.
v) Discuss the combined effects of drugs.
vi) Discuss the types of gene therapy.
vii) What are up-regulation and down-regulation of receptors ?
Seat
No.
[4355] – 207
B/I/13/4475
3. Write a note on the following (any three) : 15
i) Pharmacokinetic type of drug interactions
ii) G-Protein coupled receptor
iii) Plasma protein binding of drugs
iv) Antihistaminic drugs
v) Drug treatment in geriatric patient
SECTION – II
4. Discuss in detail pathophysiology of myocardial infarction. 10
OR
Define and classify diabetes mellitus. Discuss its pathophysiology and
complications.
5. Solve any five of the following : 15
i) Discuss the pathophysiology of pain.
ii) Explain the pathogenesis of Parkinson’s disease.
iii) Write the causes and pathophysiology of tuberculosis.
iv) Explain the mode of transmission of Hepatitis-B infection.
v) Discuss the pathophysiology of malaria.
vi) Explain types and symptoms of depression.
vii) Describe the types and clinical features of pneumonia.
6. Write a note on the following (any three) : 15
i) Pathophysiology of peptic ulcer.
ii) Mechanisms of carcinogenesis.
iii) Explain causes and risk factors of hypertension.
iv) Pathogenesis of bronchial asthma.
v) Epilepsy
————
Second Year B.Pharmacy Examination, 2013
(2008 Pattern)
2.7 : PHARMACOLOGY – I (Including Pathophysiology)
Time : 3 Hours Max. Marks : 80
Note : 1) All questions are compulsory.
2) Answer to the two Sections should be written in separate
answer books.
3) Neat labelled diagrams must be drawn wherever
necessary.
SECTION – I
1. Define bioavailabilty of drugs. Discuss the factors affecting bioavailability. 10
OR
Classify anti – coagulants. Discuss the pharmacology of Warfarin.
2. Solve any five of the following : 15
i) Write the characteristics of dose response curve(DRC). Explain potency
and efficacy of drugs using DRCs.
ii) Write advantages and disadvantages of oral route of drug administration.
iii) Define apparent volume of distribution (Vd). Explain clinical significance of
Vd. of drug.
iv) Write a note on Vitamin-K.
v) Discuss the combined effects of drugs.
vi) Discuss the types of gene therapy.
vii) What are up-regulation and down-regulation of receptors ?
No.
[4355] – 207
B/I/13/4475
3. Write a note on the following (any three) : 15
i) Pharmacokinetic type of drug interactions
ii) G-Protein coupled receptor
iii) Plasma protein binding of drugs
iv) Antihistaminic drugs
v) Drug treatment in geriatric patient
SECTION – II
4. Discuss in detail pathophysiology of myocardial infarction. 10
OR
Define and classify diabetes mellitus. Discuss its pathophysiology and
complications.
5. Solve any five of the following : 15
i) Discuss the pathophysiology of pain.
ii) Explain the pathogenesis of Parkinson’s disease.
iii) Write the causes and pathophysiology of tuberculosis.
iv) Explain the mode of transmission of Hepatitis-B infection.
v) Discuss the pathophysiology of malaria.
vi) Explain types and symptoms of depression.
vii) Describe the types and clinical features of pneumonia.
6. Write a note on the following (any three) : 15
i) Pathophysiology of peptic ulcer.
ii) Mechanisms of carcinogenesis.
iii) Explain causes and risk factors of hypertension.
iv) Pathogenesis of bronchial asthma.
v) Epilepsy
————
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