Monday, December 28, 2015

2010 Question Paper,Third Year B.Pharmacy,University Of Pune Question Paper,PHARMACEUTICAL ANALYSIS – II

University Of Pune Question Paper
Third Year B.Pharmacy Examination, 2010
PHARMACEUTICAL ANALYSIS – II
(2004 Course)
Time : 3 Hours
Max. Marks : 80
 Instructions: 1) Question Nos. 1 and 5 are compulsory. Out of the
remaining attempt 2 questions from Section I and 2
questions from Section II.
2) Answers to the two Sections should be written in separate
answer books.
3) Neat diagram must be drawn wherever necessary.
4) Black figures to the right indicate full marks.
SECTION – I
1. A) What is EMR ? Give the wave properties of it. Classify different analytical
methods based on interaction of EMR with material to be analyzed. 7
B) Explain choice of solvent in UV – vis spectroscopy. 3
2. A) What is linear scale polarography ? Describe various factors affecting limiting
current in polarography. 8
B) Draw neat diagram of polarimeter. How angle of rotation of compound is
determined. 7
3. A) What are the different electrodes used in potentiometry ? State and explain
different methods of end point detection for potentiometry. 8
B) Explain working of combined glass electrode with the help of neat diagram. 7
4. A) What are the different thermal methods of analysis ? Explain factors affecting
thermo gravimetric results. 7
B) Explain how Nephelometry and Turbidometry differs. Give Instrumentation
and application of turbidometric analysis. 8
SECTION – II
5. A) Explain how chromatography is superior separation technique. Write about
selection of chromatographic methods of analysis. 6
B) What are adsorbents used in TLC ? 2
C) What is grain direction and capacity factor ? 2
6. A) State principle of fluorometry. Draw a neat labeled diagram of fluorometer. 7
B) Explain terms : 4
a) Internal conversion
b) Intersystem crossing.
C) Explain factors affecting fluorescence. 4
7. A) Explain Van Deemters equation in detail. How it helps to improve column
performance. 5
B) Write theory UV of visible spectroscopy. 5
C) Write about measurement of angle of refraction. 5
8. Write a note on any three : 15
a) Amperometric titrations
b) Principle and theory of Radioimmunoassay
c) Derivative spectrophotometry
d) Dropping mercury Electrode.
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