PHARMACOLOGY – III (Including Clinical),Fourth Year B.Pharmacy,2010 Question Paper,University Of Pune Question Paper

University Of Pune Question Paper
Fourth Year B.Pharmacy Examination, 2010
PHARMACOLOGY – III (Including Clinical)
(2004 Course)
Time : 3 Hours Max. Marks : 80
 Instructions : 1) Question number 1 and 5 are compulsory. Out of the
remaining attempt any 2 questions from Section I and 2
questions from Section II.
2) Answers to the two Sections should be written in separate
book.
3) Figures to the right indicate full marks.
SECTION – I
1. Classify the drugs used for the treatment of myocardial ischemia. Explain in
detail pharmacology of organic nitrates. 12
2. Classify antituberculor agents. Explain in detail chemotherapy of tuberculosis.
Add a note on drugs used for mycobacterium avium complex. 14
3. Classify anticancer agents. Write in detail pharmacology of any one alkylating
agent. 14
4. Write a note on any two : 14
A) Non-pharmacological therapy of hypertension.
B) Superinfections.
C) Epipodophyllotoxins.
SECTION – II
5. Explain in detail types and phases of clinical trials. Discuss in detail design and
interpretations of double blind placebo control clinical trials. 12
6. What are the limitations of bioassays ? Explain the design and detail procedure of
bioassay of titanus antitoxin. 14
7. A) Explain in detail local and systemic toxicities. 14
B) Add a detail note on factors influencing toxicity of drugs.
8. Write a note on any two : 14
A) Prevention and treatment of poisoning.
B) Adverse drug reactions.
C) Treatment of arsenic poisoning.
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