Dr. MGR University PAPER IV PHARMACOLOGY I 2012 to 2015 Question Papers

Dr. MGR University APRIL 2012  Question Paper
Subject : PAPER IV – PHARMACOLOGY – I

[LA 810] Sub. Code: 3810
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
SECOND YEAR
PAPER IV – PHARMACOLOGY – I
Q.P. Code: 383810
Time: Three Hours Maximum: 100 marks
Answer ALL questions in the same order.
I. Elaborate on : Pages Time Marks
 (Max.) (Max.) (Max.)
 1. Describe the types of cholinoceptors (4). 17 40 min. 20
 Classify the cholinergic agonist (8).
 Write briefly about its pharmacological actions (8).
 2. Define Parkinsonism (2). 17 40 min. 20
 Classify the antiparkinsonian drugs (4).
 Write the mechanism of action (6),
 drug interactions(4) and uses of dopamine precursors (4).
II. Write notes on :
 1. Write briefly about the phases involved in Bio-transformation. 4 10 min. 6
 2. Explain the stages of general anaesthesia. 4 10 min. 6
 3. Mention the therapeutic uses of digitalis in the case of
 congestive heart failure. 4 10 min. 6
 4. Explain the Dopamine theory of Schizophrenia. 4 10 min. 6
 5. Classify Central Nervous System stimulants(3) and
 Write the mechanism of action of psychostimulants. (3) 4 10 min. 6
 6. Write the clinical uses of Nitrates in angina. 4 10 min. 6
 7. Write a note on HMG-CoA reductase inhibitors. 4 10 min. 6
 8. Describe the various routes of drug administration. 4 10 min. 6
 9. Write the synthesis, storage and metabolism of
 5-Hydroxytryptamine 4 10 min. 6
10. Write the pharmacological actions of COX-2 inhibitors 4 10 min. 6
 *******

Dr. MGR University OCTOBER 2012  Question Paper
Subject : PAPER IV – PHARMACOLOGY – I

[LB 810] Sub. Code: 3810
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
SECOND YEAR
PAPER IV – PHARMACOLOGY – I
Q.P. Code: 383810
Time: Three Hours Maximum: 100 marks
Answer ALL questions in the same order.
I. Elaborate on : Pages Time Marks
 (Max.) (Max.) (Max.)
 1. Define biotransformation.
 Discuss the synthetic and non synthetic reaction of drug
 metabolism with suitable example. 17 40 min. 20
 2. Define and classify anticholinergic agents.
 Explain the pharmacological actions, side effects,
 drug interactions and uses of Atropine. 17 40 min. 20
II. Write notes on :
 1. List out the drugs used in the treatment of Congestive Heart Failure
 and write the mechanism of Cardiac glycosides. 4 10 min. 6
 2. Define and classify local anaesthetics.
 Write the mechanism of action and uses of lignocaine. 4 10 min. 6
 3. Define the following and give example. 4 10 min. 6
 (i) Expectorants.
 (ii) Mucolytics.
 4. Write notes on oral contraceptives. 4 10 min. 6
 5. Classify anti histamines and add note on histamine receptors. 4 10 min. 6
 6. Define sedative and hypnotics.
 Write the mechanism of action of barbiturates. 4 10 min. 6
 7. Define acute toxicity, sub acute toxicity and chronic toxicity. 4 10 min. 6
 8. Write the mechanism of action and uses of Disulfirm. 4 10 min. 6
 9. Define the term mydriactics and miotics. Give example. 4 10 min. 6
10. Write notes on insulin and its preparations. 4 10 min. 6
 *******

Dr. MGR University APRIL 2013  Question Paper
Subject : PAPER IV – PHARMACOLOGY – I

[LC 810] Sub. Code: 3810
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
SECOND YEAR
 PAPER IV – PHARMACOLOGY – I
Q.P. Code: 383810
Time: Three Hours Maximum: 100 marks
 Answer All questions
I. Elaborate on: (2 x 20 = 40)
 1. a) Classify adrenergic drugs.
 Discuss about adrenergic receptors types and its locations.
 b) Explain the pharmacological actions and therapeutic uses of catecholamine.
 2. a) Classify sedative and hypnotics and write the mechanism of barbiturates.
 b) Explain the pharmacological actions, adverse effects and therapeutic uses of
 barbiturates.
II. Write notes on: (10 x 6 = 60)
 1. Classify β-adrenergic blocking agents and pharmacological action of propranolol.
 2. Briefly discuss about the stages of general anaesthesia.
 3. Write notes on microsomal enzyme induction.
 4. Classify non-steroidal anti-inflammatory drugs.
 5. Write the mode of action of digitalis.
 6. What is angine pectroris and discuss briefly its type.
 7. Classify anti-anxiety drugs.
 8. Define epilepsy and write the mode of action of phenytoin.
 9. Classify anti-cholinestrase and write its mechanism of action.
10. Write the reason for the combination of carbidopa and levodopa.
*******

Dr. MGR University OCTOBER 2013  Question Paper
Subject : PAPER IV – PHARMACOLOGY – I

[LD 810] Sub. Code: 3810
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
SECOND YEAR
PAPER IV – PHARMACOLOGY – I
Q.P. Code: 383810
Time: Three Hours Maximum: 70 marks
 Answer All questions
I. Elaborate on: (2 x 20 = 40)
 1. a) Define arrhythmias.
 b) Write the classification of antiarrythmics.
 c) Enumerate mechanism of action, adverse effects, pharmacological action and
 uses of any one class of antiarrythmics.
 2. Enumerate various factors modifying the drug effects.
II. Write notes on: (10 x 3 = 30)
 1. Insulin analogues and their Pharmacological action and uses.
 2. Write a note on local anaesthetics and their uses.
 3. Pre anaesthetic medication.
 4. Write the adverse effects, pharmacological action and uses of antianginal drugs.
 5. What are psychotropic drugs?
 6. What are nasal decongestants? Give examples.
 7. Write the pharmacological action of muscarinic cholinergic receptor blockers
 8. Pharmacodynamics.
 9. Write the mechanism adverse effects of diazepam?
10. What are anti inflammatory drugs?
*******

Dr. MGR University APRIL 2014  Question Paper
Subject : PAPER IV – PHARMACOLOGY – I

[LE 810] Sub. Code: 3810
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
SECOND YEAR
PAPER IV – PHARMACOLOGY – I
Q.P. Code: 383810
Time: Three Hours Maximum: 70 marks
 Answer All questions
I. Elaborate on: (2 x 20 = 40)
 1. a) Define congestive cardiac failure.
 b) Classify drugs used in the treatment of congestive cardiac failure.
 c) Write the mechanism of action of Digoxin.
 d) Mention its adverse effects of digoxin.
 2. What is epilepsy? Classify them. Write the classification of antiepileptics,
 Enumerate any one class with Mechanism of action, adverse effects and
 pharmacological action.
II. Write notes on: (10 x 3 = 30)
 1. Write a note on antihistamines and their uses.
 2. What is anti myasthenia gravis?
 What are anti myastheniac drugs and add note on its adverse effects.
 3. Write the adverse effects, pharmacological action and uses of angiotensin.
 converting enzyme inhibitors.
 4. What are antithyroid drugs. Write the uses of the same.
 5. What are mucolytics? give examples.
 6. Write the pharmacological action of β adrenergic receptor blockers.
 7. Drug interactions.
 8. Why levodopa combined with carbidopa?
 9. What are oral contraceptives?
10. Define sedatives and hypnotics
*******

Dr. MGR University APRIL 2015  Question Paper
Subject : PAPER IV – PHARMACOLOGY – I

[LG 810] Sub. Code: 3810
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
SECOND YEAR
PAPER IV – PHARMACOLOGY – I
Q.P. Code: 383810
Time: Three Hours Maximum: 70 marks
 Answer All questions
I. Elaborate on: (4 x 10 = 40)
 1. a) Classify drugs in Parkinson’s disease.
 b) Write the pharmacological actions of L-dopa on CNS.
 c) Write the adverse effects of L-dopa at the initiation of therapy and after prolonged
 therapy.
 2. Write with examples, biotransformation reactions involving microsomal and
 non-microsomal enzymes.
 3. a) Classify antihistamines.
 b) Write the pharmacological actions, adverse effects and therapeutic uses.
 4. a) Brief on the steps involved in the synthesis of thyroid hormones.
 b) Classify thyroid inhibitors and write its therapeutic uses.
II. Write notes on: (6 x 5 = 30)
 1. Write on different routes of drug administration.
 2. Classify anti-hypertensive drugs.
 3. Briefly discuss the therapeutic applications of local anesthetics.
 4. Write the pharmacological actions and therapeutic uses of oxytocin.
 5. What is vasomotor reversal of Dale?
 6. Compare and contrast barbiturates and benzodiazepines.
*******

Dr. MGR University OCTOBER 2015  Question Paper
Subject : PAPER IV – PHARMACOLOGY – I

[LH 810] Sub. Code: 3810
PHARM. D DEGREE EXAMINATION
(2009-2010 Regulation)
SECOND YEAR
PAPER IV – PHARMACOLOGY - I
Q.P. Code : 383810
Time: Three Hours Maximum: 70 marks
Answer ALL questions
I. Elaborate on : (4 x 10 = 40)
 1. (a) Define general anesthesia.
 (b) Classify general anesthetics.
 (c) Write the hypothesis of general anesthesia and the different stages of anesthesia.
 2. Write in detail, the factors modifying drug effects.
 3. (a) Classify adrenergic drugs.
 (b) Write the pharmacological actions and therapeutic uses of adrenaline.
 4. (a) Write the sources of cardiac glycosides.
 (b) Write the mechanism of action of digitalis and its pharmacological actions on
 cardiovascular system.
II. Write notes on : (6 x 5 = 30)
 1. Define mydriasis and write the effect of atropine on eye.
 2. Classify anti-depressants.
 3. Define cough and write briefly on drugs used in cough.
 4. Define diabetes mellitus and add a note on hypoglycemic agents.
 5. Write on opioid analgesics.
 6. Write on pre-clinical evaluations.
******* 

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