SECOND M.B.B.S.,Paper I – GENERAL PATHOLOGY AND HAEMATOLOGY,Dr. MGR University Question Paper,2012 Question Paper

Dr. MGR University Question Paper
SECOND M.B.B.S. DEGREE EXAMINATION
Revised (Non-Semester) Regulations
Paper I – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time: Three Hours Maximum: 40 Marks
Answer ALL questions in the same order.
Draw Suitable diagrams wherever necessary
I. Elaborate on :
 1. Define shock. Discuss in detail the pathogenesis of septic shock.
 Describe the morphology of kidneys and lungs affected by shock. (10 x 1 = 10)
 2. 60 yrs male presented with normocytic normochromic anaemia, pathological fracture
 femur and proteinura. X ray skull revealed punched out lesions in the calvarium and
 peripheral smear studied show rouleaux formation.
a) What is your probable diagnosis.
b) Discuss in detail the molecular pathogenesis, morphology and clinical features of
 above said disorder. (5 x 1 = 5)
II. Write notes on : (10 x 1.5 = 15)
1. Turner syndrome.
2. Immune complex mediated hypersensitivity.
3. Differentiation and anaplasia.
4. Viral haemorrhagic fevers.
5. Morphology of leprosy.
6. Morphology of primary myelo fibrosis.
7. Pathogenesis of sickle cell disease.
8. Chronic immune thrombocytopaenic purpura.
9. Free radicals
 10. Defects in leucocyte function.
III. Short Answers on : (10 x 1 = 10)
1. Fat necrosis.
2. Heart failure cells.
3. Lines of zahn.
4. Warburg effect.
5. Mott cells.
6. 4 tumors associated with AIDS.
7. Cross matching.
8. Anticoagulants.
9. PSEDO PELGER HUET ANOMALY.
 10. Black water fever.
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