Dr. A.P.J. Abdul Kalam University M PHARMACY I SEM (ALL BRANCH) Cellular and Molecular Pharmacology (MPL104T) Dec 2020 Question Paper

Dr. A.P.J. Abdul Kalam University

Master of Pharmacy (Pharmacology)

First Semester Main Examination, Dec-2020

Cellular and Molecular Pharmacology (MPL104T)

Time: 3:00 Hrs Max Marks 75

Note: Attempt any five questions. All questions carry equal marks.

Q.1 (a) Give application of recombinant DNA technology.

(b) What is gene mapping and cloning of dicersc gene?

Q.2 (a) Give detail about cell culture media and various types of cell cultire with general

procedure.

(b) Explain the principle and application of call viability assays and gluwse uptake

assay.

Q.3 (a) Write a note on apoptosis.

(b) Explain signal transducer and activators of transcription (STAT) signaliy

pathway.

Q.4 (a) Write a note on intracellular signaliy pathways.

Q.5 (a) Discuss synthesis and physiological function of nitric oxide.

(b) Discuss physiology of serotenin.

Q.6 (a) Write in detail genetic variation in drug transportors.

(b) Write a note on nuclear reception

Q.7 (a) Explain transportor mechanism acnes cell membrane .

(b) Discuss signal transduction mechanism by GPCR.

Q.8 Write short note on (Any three):-

(a) Genomics

(b) Proteomics

(c) Metabolomice

(d) Functionomics

(e) Nutrigonomics

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