Dr. A.P.J. Abdul Kalam University D PHARMA II SEM PHARMACEUTICAL CHEMISTRY - II [DPY202] April 2021 Question Paper

Dr. A.P.J. Abdul Kalam University

Diploma in Pharmacy

Second Year Main Examination, April-2021

PHARMACEUTICAL CHEMISTRY - II [DPY202]

Time: 3:00 Hrs Max Marks 80

Note : Attempt any five questions.

Each question carries equal marks.

Q.1 (a) Fill in the blanks with suitable words. (1- 10)

(i) Diabetes mellitus is a metabolic disorder which is caused by_________ deficiency.

(ii) Mebendazole is an example of___________________

(iii) Biological source of Actinomycin is ________________

(vi) Erythromycin is an example of___________________ antibiotic.

(v) Biperiden is a__________________ antagonist.

(vi) Procaine is an example of_____________ drug.

(vii) Hypoglycemic agent____________ blood sugar level.

(viii) Biological sources of Penicillin is ________________

Q. 1 (b) Multiple Choice Question-

(i) Emetine is used in the treatment of -

(a) Malaria (b) Tuberculosis

(c) Amebiasis (d) None of the above

(ii) Which one of these is a first line drug to treat tuberculosis -

(a) PAS (b) Rifampin

(c) Ethambutol (d) Ethionamide

(iii) Naltrexone is a morphine

(a) Agonist (b) Antagonist

(c) Partial antagonist (d) All of the above

(iv) Oxazepam is a metabolite of

(a) Diazepam (b) Lorazepam

(c) Chlordiazepoxide and diazepam (d) Alprozolam

(v) The tetracycline with highest antileprotic activity is

(a) Docycycline (b) Oxytetracycine

(c) Methacycline (d) Minocycline

(vi) Piperazine citrate is used as

(a) Antimalerial (b) Anthemintic

(c) Metabolite antagoinst (d) Amoebicidal

(vii) The inhalation anesthetic with the fastest onset of action is

(a) Nitrous oxide (b) Enflurane

(c) Isoflurane (d) Nitric oxide

(viii) The recent antifungal agent for topical use is

(a) Nystatin (b) Amphotericin B

(c) Ketoconazole (d) Fluconazole

(ix) Indirectly acting sympathomimatic Shock is

(a) Dopamine (b) Tyramine

(c) Phenylephrine (d) Isoprenaline

(x) Which of the following is most effective antitubercular drug?

(a) INH (b) PAS

(c) Streptomycin (d) Ethambutol

Q.2 (a) Write about antiseptic and Disinfectants?

(b) Write about tranquilizers?

Q.3 (a) Write about anthelmintic drugs with examples?

(b) Describe the chemistry and uses of any two antimalarial drugs?

Q.4 (a) Describe cholinergic drugs.

(b) Describe the chemical structure, nomenclature and uses of Indomethacin?

Q.5 (a) Write the synthesis of Neostigmine?

(b) Explain the diuretic drugs with example. Write the synthesis of ethylnitrite.

Q.6 (a) Explain Anti- neoplastic drugs with example. Write the properties and uses of actinomycin?

(b) Write note on- i) Diagonostic Agent & ii) Hypoglycemic Agent.

Q.7 (a) Write a detail note on Adrenergic Antagonist.

(b) What are NSAIDs? Classify them & draw three structure belonging this category?

Q.8 (a) Give detail account of CNS stimulants with example.

(b) Write a descriptive note on Antimalarial Drug.

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